Osama Chahrour

Osama Chahrour joined Fera as Analytical Chemistry Team Leader to provide support to our current range of investigative programs, and develop our existing reputation as the ‘go to’ lab for challenging small molecule mass spectroscopy applications.

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  • Area of expertise
    Analytical Chemistry
  • Years of experience
    14
  • Highest qualification
    PhD

Osama Chahrour joined Fera as Analytical Chemistry Team Leader to provide support to our current range of investigative programs, and develop our existing reputation as the ‘go to’ lab for challenging small molecule mass spectroscopy applications.

Osama’s most important duties within his role will be to manage investigative programs, GLP studies and regulatory studies, providing technical support and reporting directly to the board on these projects. He also has the responsibility to manage the safety and cases for capital expenditure in the GC-MS facility.

Before joining Fera, Osama progressed from being a Senior Analytical Chemist-Mass Spectroscopy to the role of Team Leader at Almac UK.

Osama has a strong background in implementing mass spec techniques to serve analytical purposes, such as: quantification of contaminates, metabolite identification/quantification, and trace impurity structural elucidation.

More about chemical regulation

Regulations and restrictions on the use of chemicals to tackle plant and animal pests and diseases are becoming increasingly stringent, which means the range of chemical options available for tackling these threats is constantly being eroded. It’s essential to ensure that any chemicals used in the environment do not pose a threat to plants, wildlife and ecosystems, while ensuring they are effective against target pests and diseases.


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Writing
Services

Latest Papers and Articles

O. Chahrour, A. Abdalla, F. Lam, C. Midgley, and S. Wang, “Synthesis and biological evaluation of benzyl styrylsulfonyl derivatives as potent anticancer mitotic inhibitors,” Bioorganic Med. Chem. Lett., vol. 21, no. 10, pp. 3066–3069, 2011.

O. Chahrour and J. Malone, “Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Applications in Quantitative Proteomics,” Protein Pept. Lett., vol. 24, no. 3, pp. 253–266, Jan. 2017.

O. Chahrour, D. Cobice, and J. Malone, “Stable isotope labelling methods in mass spectrometry-based quantitative proteomics,” J. Pharm. Biomed. Anal., vol. 113, pp. 2–20, 2015.

T. Lu, A. W. Goh, M. Yu, J. Adams, F. Lam, T. Teo, P. Li, B. Noll, L. Zhong, S. Diab, O. Chahrour, A. Hu, A. Y. Abbas, X. Liu, S. Huang, C. J. Sumby, R. Milne, C. Midgley, and S. Wang, “Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: Synthesis, structure-activity relationships, and biological activities,” J. Med. Chem., vol. 57, no. 6, pp. 2275–2291, 2014.

O. Chahrour, D. Cairns, and Z. Omran, “Small molecule kinase inhibitors as anti-cancer therapeutics.,” Mini Rev. Med. Chem., vol. 12, no. 5, pp. 399–411, May 2012.

P. Labarbuta, K. Duckett, C. H. Botting, O. Chahrour, J. Malone, J. P. Dalton, and C. J. Law, “Recombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe2+/H+exchanger,” Sci. Rep., vol. 7, p. 42850, Feb. 2017.

O. Chahrour, J. Malone, M. Collins, V. Salmon, C. Greenan, A. Bombardier, Z. Ma, and N. Dunwoody, “Development and validation of an ICP-MS method for the determination of elemental impurities in TP-6076 active pharmaceutical ingredient (API) according to USP 〈232〉/〈233〉,” J. Pharm. Biomed. Anal., vol. 145, pp. 84–90, Oct. 2017.

Shudong Wang; Nottinghamshire (GB);, Osama Chahrour; Nottinghamshire, (GB); Tiangong Lu; Nottinghamshire, and (GB); Anran Hu; Nottinghamshire (GB), “COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS,” US 2013/0190325 A1, 2013.

Osama and their team work with customers to deliver the following services within Fera...


Ecotoxicology

Helping commercial companies to accurately assess the toxic impacts of plant-protection products and veterinary medicines on a range of ecosystems and species.

Learn more

Consultancy

Fera consultancy services support you through the regulatory processes required to register your chemical products and biocides in the EU.

Learn more

Environmental Fate

Regulations-compliant environmental fate studies provide essential data on the fate and behaviour of a range of chemicals in the environment including pesticides.

Learn more

Our Chemical Regulatory Work
Writing

Latest Papers and Articles

O. Chahrour, A. Abdalla, F. Lam, C. Midgley, and S. Wang, “Synthesis and biological evaluation of benzyl styrylsulfonyl derivatives as potent anticancer mitotic inhibitors,” Bioorganic Med. Chem. Lett., vol. 21, no. 10, pp. 3066–3069, 2011.

O. Chahrour and J. Malone, “Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Applications in Quantitative Proteomics,” Protein Pept. Lett., vol. 24, no. 3, pp. 253–266, Jan. 2017.

O. Chahrour, D. Cobice, and J. Malone, “Stable isotope labelling methods in mass spectrometry-based quantitative proteomics,” J. Pharm. Biomed. Anal., vol. 113, pp. 2–20, 2015.

T. Lu, A. W. Goh, M. Yu, J. Adams, F. Lam, T. Teo, P. Li, B. Noll, L. Zhong, S. Diab, O. Chahrour, A. Hu, A. Y. Abbas, X. Liu, S. Huang, C. J. Sumby, R. Milne, C. Midgley, and S. Wang, “Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: Synthesis, structure-activity relationships, and biological activities,” J. Med. Chem., vol. 57, no. 6, pp. 2275–2291, 2014.

O. Chahrour, D. Cairns, and Z. Omran, “Small molecule kinase inhibitors as anti-cancer therapeutics.,” Mini Rev. Med. Chem., vol. 12, no. 5, pp. 399–411, May 2012.

P. Labarbuta, K. Duckett, C. H. Botting, O. Chahrour, J. Malone, J. P. Dalton, and C. J. Law, “Recombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe2+/H+exchanger,” Sci. Rep., vol. 7, p. 42850, Feb. 2017.

O. Chahrour, J. Malone, M. Collins, V. Salmon, C. Greenan, A. Bombardier, Z. Ma, and N. Dunwoody, “Development and validation of an ICP-MS method for the determination of elemental impurities in TP-6076 active pharmaceutical ingredient (API) according to USP 〈232〉/〈233〉,” J. Pharm. Biomed. Anal., vol. 145, pp. 84–90, Oct. 2017.

Shudong Wang; Nottinghamshire (GB);, Osama Chahrour; Nottinghamshire, (GB); Tiangong Lu; Nottinghamshire, and (GB); Anran Hu; Nottinghamshire (GB), “COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS,” US 2013/0190325 A1, 2013.

Services

Osama and their team work with customers to deliver the following services within Fera...


Ecotoxicology

Helping commercial companies to accurately assess the toxic impacts of plant-protection products and veterinary medicines on a range of ecosystems and species.

Learn more

Consultancy

Fera consultancy services support you through the regulatory processes required to register your chemical products and biocides in the EU.

Learn more

Environmental Fate

Regulations-compliant environmental fate studies provide essential data on the fate and behaviour of a range of chemicals in the environment including pesticides.

Learn more

Our Chemical Regulatory Work

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