Antimicrobial substances are commonly used by producers to support animal welfare. Their ability to control and prevent disease, as well as increasing weight gain, has led to widespread use within the agricultural industry.
The monitoring of residues of authorised veterinary medicines is important to ensure that residues that exceed established legal limits do not enter the food chain. Maximum Residue Limits (MRLs) have been defined for antimicrobial substances in Commission Regulation (EU) 37/2010 and subsequent amendments.
Testing is carried out using liquid chromatography–tandem mass spectrometry (LC–MS/MS), and has been validated in accordance with the principles set out in Commission Decision 2002/657/EC, for the majority of analyte / matrix combinations.
|Veterinary Medicine Group||Veterinary Medicine|
|b-lactams||Amoxicillin, Ampicillin, Cloxacillin, Dicloxacillin, Nafcillin, Oxacillin, Penicillin G, Penicillin V|
|Cephalosporins [milk]||Cefalexin, Cefalonium, Cefapirin, Cefazolin, Cefoperazone, Cefquinome, Ceftiofur Desacetylcephapirin|
|Macrolides||3-0-Acetyltylosin, Ciprofloxacin, Dapsone, Erythromycin, Gamithromycin, Josamycin, Lincomycin, Pirlimycin, Spiramycin, Tildipirosin, Tilmicosin, Tulathromycin, Tylosin, Tylvalosin, Virginiamycin|
|Quinolones||Danofloxacin, Difloxacin, Enrofloxacin, Flumequine, Marbofloxacin, Nalidixic acid, Norfloxacin, Oxolinic acid, Sarafloxacin|
|Sulfonamides||Sulfachloropyridazine, Sulfadiazine, Sulfadimethoxine, Sulfadoxine, Sulfaguanidine, Sulfamerazine, Sulfamethazine, Sulfamethizole, Sulfamethoxazole, Sulfamethoxypyridazine, Sulfamonomethoxine, Sulfamoxole, Sulfanilamide, Sulfapyridine, Sulfaquinoxaline, Sulfathiazole, Sulfisoxazole, Trimethoprim|
|Tetracyclines||Chlortetracycline, 4-Epichlortetracycline, Doxycycline, Oxytetracycline, 4-Epioxytetracycline, Tetracycline, 4-Epitetracycline|
For the full list of veterinary medicines we can test for please follow the link below:
The use of LC-MS/MS for screening has advantages over the traditional tests based on microbial growth inhibition. The identity of any substance present can be unequivocally confirmed, along with an estimation of the concentration present. There is therefore no requirement for repeat analyses due to false positives which are prevalent in microbial growth inhibition tests.
Standard Turnaround Time
|10 working days|
LOD (limit of detection)
|Meets or exceeds EU legislative requirements|
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