Environmental Fate & Metabolism Studies

  • Environmental safety and risk testing can be a very complex and lengthy process on your path to registration. Working with a partner who understand the regulatory landscape is vital for success.
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Environmental Fate & Metabolism Studies


The importance of Environmental Fate & Metabolism Studies

Environmental fate studies are key to providing the data required by chemical companies to complete thorough environmental risk assessments (ERA). They provide information on the fate and behaviour of chemical products in the environment, and contribute to the determination of the risk posed to human and environmental health.  Metabolism studies are conducted to determine the nature of residues and the test substance’s metabolic pathways in animals.


By Sector

plant protection products
Plant Protection Products (PPP)

See how Fera can help you expedite the discovery, early-stage development and safe manufacture of novel products for crop protection.

Work with a partner you can rely on.

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Veterinary medicines
Veterinary Medicines

Working with world-class facilities and instrumentation, applying decades of experience in regulatory consultancy to empower you to meet your veterinary medicines challenges.

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If you are a company developing veterinary products or plant protection products (PPPs), it’s essential that you fully assess the risks posed by your products to the wider environment and natural ecosystems. In the face of ever-tightening regulation and restrictions on the chemical options available, Fera can help you to develop effective, sustainable products that minimise ecosystem impacts and pollution, while maximising the beneficial effects for crops, plants and animals.  

Our services and expertise provide essential support on your road to successful product registrations and ongoing due diligence – whether for pesticides, veterinary medicines or pharmaceuticals. We provide a range of services from single studies to complex, whole programmes, including dossier preparation and submission.  An understanding of the environmental fate processes can ensure that your applications are not only effective, but are also environmentally safe, providing you with the data you need to make product development decisions and obtain product registrations. Our multidisciplinary teams combine decades of agrochemical and veterinary drug industry experience with world-class technical expertise and analytical capabilities. We operate in GLP-compliant facilities with the UK providing regulatory compliant studies for submission in all geographic regions.


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Environmental Fate Studies

Chemical impact assessment is critical for the protection of the aquatic environment. It is important that testing assesses each of the trophic levels; photosynthetic organisms, herbivores and predatory organisms, including fish. 

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Animal Metabolism Studies

We work with partners to design and plan every detail of a study to best meet the product development and/or regulatory compliance needs.  Our GLP-compliant studies range from preliminary tests to determining the uptake of 14C radiolabelled agrochemicals and metabolite profiles. 

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Plant Metabolism Studies

Using a wealth of experience gained supporting plant breeders, agrochemical and biopesticide manufacturing industries, Fera Science is able to perform OECD and GLP compliant plant metabolism studies our  state-of-the-art facilities in the UK. 


Plant Uptake Factor Studies

Plant Uptake Studies

Fera's Plant Uptake Studies brings together Radiochemistry, Plant Growth & Modelling knowledge to support chemical regulatory assessments & used with Environmental Fate Models such as PEARL, PELMO or PRZM to represent the proportion of chemical absorbed into the plant via the roots.

Pesticide usage survey

Pesticide Usage Survey

Fera is commissioned to conduct agricultural, horticultural and amenity pesticide usage surveys by the Chemicals Regulation Division (CRD) of the Health and Safety Executive (HSE). The surveys are funded from the pesticides charge on industry turnover.

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Regulatory Risk Assessment

Access to experienced senior scientists across all scientific disciplines, we understand the relevant legislative frameworks and are uniquely positioned to assist you meet the regulatory requirements for crop protection registrations.


Fera’s environmental fate studies include a range of regulatory compliant tests to assess the biodegradation of chemicals in soil and water. By understanding how chemical products are broken down and degraded in the natural environment, we can supply the data you need for your environmental risk assessments – ensuring you meet all regulatory requirements in the development of safe new chemical products. With improved capacity of 300%, as more parent-associated metabolite fate studies become necessary, we can offer the entire spectrum of laboratory and higher-tier environmental fate studies with more efficient turnaround times.  We’re committed to helping clients get more products to market with investment in our people and more efficient equipment to provide bespoke and innovative solutions.

Our investment in our HPLC lab provides customers with a more efficient and cost effective service. With our SoFie™ modules we can detect smaller levels of radioactivity due to the stop-flow mechanism. With improved sensitivity of signal to noise SoFie™ gives better counting statistics without adversely affecting the chromatography.  We also offer a range of bespoke studies, which meet regulatory requirements. We can tailor the design of standard recognised regulatory studies to meet your specific objectives. Our scientists will work with you to understand the requirements of your ERA, and can amend the test matrix, design and analysis to suit the analyte in question. Our expert team supports you through the entire regulatory process, from answering questions about compound formulation to fielding regulator queries on submitted risk assessments.

Meet some of the team

Eleanor Walker

Eleanor Walker

Eleanor is the Environmental Fate and Metabolism Laboratory Manager at Fera ensuring the laboratories and procedures performed are GLP compliant. Eleanor makes sure that the work produced is of high quality and actively investigates the improvement of our capabilities to suit customer requirements.

Meet the scientists

Phil Rooney

Phil is the senior environmental fate scientist for chemical safety at Fera with 10 years’ experience in the area. With a background in biochemistry, Phil manages commercial and research projects within the environmental fate and behaviour sector. 

IAFRI partnership

Chris Sinclair

Chris is an expert in regulatory environmental risk assessment processes, registration requirements and guidance for pharmaceuticals, veterinary medicines and pesticides.


GLP-compliant laboratories

Our laboratories are equipped with state-of-the-art facilities that enable cost-effective GLP-compliant environmental fate studies to be performed, in line with all regulatory requirements, including:

  • Laboratory (GLP) analytical services for agrochemicals, biocides, and veterinary medicinal products.
  • Laboratory studies with radio-labelled and non-radiolabelled chemicals.
  • Batch sorption, including aged sorption and column leaching studies according to OECD guidelines, as well as parameter estimation.
  • Soil, water-sediment and manure/slurry biodegradation studies, including estimation of degradation parameters and endpoints.
  • Hard (man-made) surfaces fate studies, including lab-scale sorption, wash-off and field monitoring studies.
  • Design, interpretation and analysis of lysimeter, field leaching, field dissipation and environmental (e.g. groundwater) monitoring studies.
  • Find out more about about the facilities we have onsite at Fera - click the link below;
Our facilities


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Registered Office: 30 Berners Street, London, W1T 3LR. Registered in England & Wales, No 9413107. Fera is a joint venture company of Capita Plc, 30 Berners Street, London, W1T 3LR. Registered in England and Wales No 02081330. VAT Registration ID: GB 618184140
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